ERNDIMQA - Special Assays in Urine

Purpose: Comparison of outcome of a heterogeneous group of lab-assays, relevant to the diagnosis of inborn errors of metabolism, in respect to median and target values. In addition recovery of added analyte, precision and analytical linearity are tested.
Scientific Expert: Dr. Rafael Artuch
Scheme Organiser: MCA
Analytes: 4-OH-Glutamic acids, 5-Aminoluvelinic acid, 5-OH-Indolacetic acid (5HIAA), Carnitine Free, Creatine, Creatinine, D, L-Glyceric acid, Galactitol, Glycolic acid,  Guanidinoacetate, Homocitrulline, Homogentisic acid, Homovanillic acid (HVA), Lactic acid,  L-Cystine, MPS (condroitin sulfate),  Orotic acid, Oxalic acid, Pipecolic acid, Sialic acid, Succinylacetone and Sulfocysteine (2023).
Number of Specimens/Year: 8
Matrix of the Specimens: Lyophilised spiked human urine
Volume/Specimen: 5 mL/vial
Number of Shipments/Year: One shipment of 8 specimens in February
Submission of Results: Online via ERNDIM-MCA website
Reports: Requested from ERNDIM-MCA website
Certificate: Once a year issued by ERNDIM Board
Number of Participants: 194 (2023)
Status of the Scheme: Operated since 1993
Geographic Area: Worldwide
Limitation Participation: None
Cost/Year: 204 EURO / 375 EURO in combination with Special Assays in Serum (2023)
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